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Shatter Non-Compliance with HIGH Tolerability

A Strong Safety Profile Without Compromise

Through 36 months1,2*: 

0

  • No clinically significant endothelial cell loss
  • No periorbital fat atrophy
  • No serious corneal AEs
  • No DSAEK
  • No DMEK

Implant designed to remain fixed & stable

positioned parallel to the iris, away from the corneal endothelium3

The Most Commonly Reported Ocular Adverse Reactions (2%-6%)3 

Most Adverse Reactions were Mild or Moderate and Resolved4

Phase 2b and Phase 3 Trials Combined Through 12 months | N=868

  • Increases in intraocular pressure
  • Eye pain
  • Iritis
  • Ocular hyperemia
  • Dry eye
  • Reduced visual acuity
  • Visual field defects

Includes both slow-eluting and fast-eluting implants. The slow-eluting implant is the only approved and commercially marketed version. 

iDOSE TR
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1. iDose TR Phase 3 Clinical Trials, data on file, Glaukos Corporation.
2. Berdahl JP, et al. Efficacy and Safety of the Travoprost Intraocular Implant in Reducing Topical IOP-Lowering Medication Burden in Patients with Open-Angle Glaucoma or Ocular Hypertension. Drugs. 2023 Dec 7. doi: 10.1007/s40265-023-01973-7. PMID: 38060092.
3. iDose TR (travoprost intracameral implant) 75 mcg Prescribing Information. Glaukos Corporation. 2023.
4. Data on file, Glaukos Corporation.
* Inclusive of Phase 3 and Phase 2b trials

Important Safety Information

Dosage And Administration

For ophthalmic intracameral administration. The intracameral administration should be carried out under standard aseptic conditions.

Contraindications

iDose TR is contraindicated in patients with active or suspected ocular or periocular infections, patients with corneal endothelial cell dystrophy (e.g., Fuch’s Dystrophy, corneal guttatae), patients with prior corneal transplantation, or endothelial cell transplants (e.g., Descemet’s Stripping Automated Endothelial Keratoplasty [DSAEK]), patients with hypersensitivity to travoprost or to any other components of the product.

Warnings And Precautions

iDose TR should be used with caution in patients with narrow angles or other angle abnormalities. Monitor patients routinely to confirm the location of the iDose TR at the site of administration. Increased pigmentation of the iris can occur. Iris pigmentation is likely to be permanent.

Adverse Reactions

In controlled studies, the most common ocular adverse reactions reported in 2% to 6% of patients were increases in intraocular pressure, iritis, dry eye, visual field defects, eye pain, ocular hyperaemia, and reduced visual acuity.

Indications And Usage

iDose TR (travoprost intracameral implant) is indicated for the reduction of intraocular pressure (IOP) in patients with open-angle glaucoma (OAG) or ocular hypertension (OHT).

Please see full Prescribing Information.

You are encouraged to report all side effects to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

You may also call Glaukos at 1-888-404-1644.

The information contained in this site is intended for US healthcare professionals only

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